Key Summary:

• Glutathione is a natural antioxidant your body produces in every cell, especially in the liver.
• It supports melanin balance, detoxification, and glow-from-within health.
• Supplements simply add extra glutathione when your natural levels drop from stress, UV exposure, and lifestyle.
• Most high-quality products use naturally derived, fermented glutathione — including Japan-formulated blends like Ishin Premium.
• This makes glutathione supplements safe, natural in function, and effective for clearer, balanced skin.
• Glutathione is natural because your body makes it; supplements just help restore what daily life depletes.

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Is Glutathione Natural or Synthetic?

Many Filipinas ask the same question when choosing a safe supplement:

“Natural ba ang glutathione or gawa sa lab?”

Here is the real answer:

✔ Glutathione itself is 100 percent natural.

Your body makes it every day inside your cells, especially in the liver.
It helps you:
• balance melanin
• detoxify
• repair damaged skin
• fight free radicals
• protect against dullness and UV stress

So yes, the molecule glutathione is natural.

But here’s the part most people don’t know:

The glutathione used in supplements can come from two very different production methods:

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🍋 3. Forms of Glutathione Used in Supplements

Your skin results depend heavily on the form used.

Best known forms:

Ishin Premium uses three types Free Form, L-Glutathione, and S-Acetyl, these all work with your body to brighten through melanin balance.

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⭐ 5. Ingredient Comparison (Permanent Feature)

These ingredients support natural brightening and glutathione function:

Ingredient	What It Does	Ideal For
Free Form Glutathione	Easiest form for daily absorption	Glow, daily brightening
L Glutathione	Most common in studies	General glow from within
S Acetyl Glutathione	Greater stability	Stronger antioxidant activity
Liposomal Glutathione	Encapsulated version	Sensitive digestion
NAC	Helps your body produce more glutathione	Dull, tired skin
L Cysteine	Glutathione precursor	Uneven tone
Vitamin C	Regenerates glutathione	Faster brightening
ALA	Recycles antioxidants	UV stressed skin

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📚 What Science Says About Natural Glutathione

Source Type	Scientific Insight	Reference
Review Article	Glutathione’s role in detoxification and antioxidant defense; includes dietary sources and supplementation insights.	Forman, H.J. et al., 2009
Dermatological Study	Support buccal/oral absorption as a safer and potentially more effective delivery route for glutathione than intravenous forms.	Rahim, N.H.A. et al., 2016
Clinical Bioavailability Study	Oral natural glutathione (GSH) increases glutathione stores in rats and humans.	Witschi, A. et al., 1992
Clinical Antioxidant Research	Evaluates the effect of natural glutathione supplementation on oxidative stress, inflammation, and immunity in humans.	Müller, M. et al., 2023

Simplified takeaway:
Glutathione is natural in your body and naturally sourced in most high quality supplements.

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💬 Frequently Asked Questions

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⭐ KEY TAKEAWAY

Glutathione is natural in your body, but not all supplement glutathione is equal. Natural fermentation-based glutathione is the safest, cleanest and most effective. Synthetic glutathione is cheaper but less stable and less trusted by the body.

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🌸 FINAL THOUGHT

Natural glutathione works with your biology.
Synthetic versions work against it.

Choose glow that your body recognizes. Choose glow that lasts.
Choose Ishin Premium.

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✨ Find Out What’s More About Our Product